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    Background:  

    RAB35 is a member of the small GTPase superfamily. Like the other Rab proteins, RAB35 has 2 consecutive 

    cysteine residues at its C terminus, and this region is thought to be involved in membrane association. Rab35 is

    found on the cell surface and endosomes, where it has been proposed to play a role in recycling of the transferrin 

    and other receptors.